Dieses Bild zeigt Pavel Bashtrykov

Pavel Bashtrykov

Herr Dr. rer. nat. Dr. med.

Gruppenleiter und Leiter Bioinformatik
Abteilung Biochemie, Institut für Biochemie und Technische Biochemie

Kontakt

+49 711 685 64363
+4971168564392

Allmandring 31
70569 Stuttgart
Deutschland
Raum: 01.165

Fachgebiet

Molekulare Epigenetik, NGS, CRISPR Genom/Epigenom Editierung, Bioinformatik

Publikationsliste von Pavel Bashtrykov bei ResearchGate

Publikationsliste von Pavel Bashtrykov bei PubMed

Publikationsliste von Pavel Bashtrykov bei Google Scholar

 

Ausgewählte Veröffentlichungen

  • Engmann O, Labonté B, Mitchell A, Bashtrykov P, Calipari ES, Rosenbluh C, Loh YE, Walker DM, Burek D, Hamilton PJ, Issler O, Neve RL, Turecki G, Hurd Y, Chess A, Shen L, Mansuy I, Jeltsch A, Akbarian S, Nestler EJ. Cocaine-Induced Chromatin Modifications Associate With Increased Expression and Three-Dimensional Looping of Auts2. Biological psychiatry. 2017.
  • Bashtrykov P, Jeltsch A. Epigenome Editing in the Brain. Advances in experimental medicine and biology. 2017; 978:409-424.
  • Bashtrykov P, Kungulovski G, Jeltsch A. Correction of aberrant imprinting by allele-specific epigenome editing. Clinical pharmacology and therapeutics. 2016; 99(5):482-4.
  • Bashtrykov P, Jeltsch A. DNMT1-associated DNA methylation changes in cancer. Cell cycle (Georgetown, Tex.). 2015; 14(1):5.
  • Bashtrykov P, Rajavelu A, Hackner B, Ragozin S, Carell T, Jeltsch A. Targeted mutagenesis results in an activation of DNA methyltransferase 1 and confirms an autoinhibitory role of its RFTS domain. Chembiochem : a European journal of chemical biology. 2014; 15(5):743-8.
  • Bashtrykov P, Jankevicius G, Jurkowska RZ, Ragozin S, Jeltsch A. The UHRF1 protein stimulates the activity and specificity of the maintenance DNA methyltransferase DNMT1 by an allosteric mechanism. The Journal of biological chemistry. 2014; 289(7):4106-15.
  • Bashtrykov P, Jankevicius G, Smarandache A, Jurkowska RZ, Ragozin S, Jeltsch A. Specificity of Dnmt1 for methylation of hemimethylated CpG sites resides in its catalytic domain. Chemistry & biology. 2012; 19(5):572-8.
  • Bashtrykov P, Ragozin S, Jeltsch A. Mechanistic details of the DNA recognition by the Dnmt1 DNA methyltransferase. FEBS letters. 2012; 586(13):1821-3.
  • Menshikov M, Plekhanova O, Cai H, Chalupsky K, Parfyonova Y, Bashtrikov P, Tkachuk V, Berk BC. Urokinase plasminogen activator stimulates vascular smooth muscle cell proliferation via redox-dependent pathways. Arteriosclerosis, thrombosis, and vascular biology. 2006; 26(4):801-7.
  • Furnkranz A, Schober A, Bochkov VN, Bashtrykov P, Kronke G, Kadl A, Binder BR, Weber C, Leitinger N. Oxidized phospholipids trigger atherogenic inflammation in murine arteries. Arteriosclerosis, thrombosis, and vascular biology. 2005; 25(3):633-8.

Leitung

  • Laborübung „Biochemische Methoden für Fortgeschrittene“
  • Seminar „Genregulation, Chromatin und Molekulare Epigenetik“
 

Beteiligung

  • Genregulation, Chromatin und Molekulare Epigenetik
  • Forschungspraktika, B.Sc. und M.Sc. Arbeiten

Education and Career

  • 2021: Dr. med., the Faculty of Medicine, Eberhard Karls University of Tübingen, Germany
  • 2019-present: Bioinformatic Leader, Department of Biochemistry, IBTB, University of Stuttgart, Germany
  • 2016-2021: Doctoral studies, the Faculty of Medicine, Eberhard Karls University of Tübingen, Germany
  • 2015-present: Group leader, Department of Biochemistry, IBTB, University of Stuttgart, Germany
  • 2014-2015: Postdoctoral position, Department of Biochemistry, IBTB, University of Stuttgart, Germany
  • 2014: Dr. rer. nat. (Biochemistry), summa cum laude
  • 2010-2014: Doctoral studies, Jacobs University (Bremen) / Department of Biochemistry, IBTB, University of Stuttgart, Germany
  • 2007-2010: Clinical Research Associate (Junior CRA, CRA, Sr. CRA), Quintiles GmbH
  • 2002: Invited Scientist, Medical University of Vienna, Department of Vascular Biology and Thrombosis Research, Vienna, Austria
  • 1999-2006: Research Assistant, Russian Cardiology Research Centre, Department of Molecular Endocrinology, Moscow, Russia
  • 2003: Diploma in Medicine
  • 1997-2003: Study of Medicine, Moscow State University, Moscow, Russia
Zum Seitenanfang