This image shows Pavel Bashtrykov

Pavel Bashtrykov


Group leader
Abteilung Biochemie, Institut für Biochemie und Technische Biochemie


+49 711 685 64363

Allmandring 31
70569 Stuttgart
Room: 01.165


Biochemie und Molekulare Epigenetik

Publication list of Pavel Bashtrykov at ResearchGate

Publication list of Pavel Bashtrykov at PubMed

Publication list of Pavel Bashtrykov at Google Scholar


Selected Publications

  • Engmann O, Labonté B, Mitchell A, Bashtrykov P, Calipari ES, Rosenbluh C, Loh YE, Walker DM, Burek D, Hamilton PJ, Issler O, Neve RL, Turecki G, Hurd Y, Chess A, Shen L, Mansuy I, Jeltsch A, Akbarian S, Nestler EJ. Cocaine-Induced Chromatin Modifications Associate With Increased Expression and Three-Dimensional Looping of Auts2. Biological psychiatry. 2017.
  • Bashtrykov P, Jeltsch A. Epigenome Editing in the Brain. Advances in experimental medicine and biology. 2017; 978:409-424.
  • Bashtrykov P, Kungulovski G, Jeltsch A. Correction of aberrant imprinting by allele-specific epigenome editing. Clinical pharmacology and therapeutics. 2016; 99(5):482-4.
  • Bashtrykov P, Jeltsch A. DNMT1-associated DNA methylation changes in cancer. Cell cycle (Georgetown, Tex.). 2015; 14(1):5.
  • Bashtrykov P, Rajavelu A, Hackner B, Ragozin S, Carell T, Jeltsch A. Targeted mutagenesis results in an activation of DNA methyltransferase 1 and confirms an autoinhibitory role of its RFTS domain. Chembiochem : a European journal of chemical biology. 2014; 15(5):743-8.
  • Bashtrykov P, Jankevicius G, Jurkowska RZ, Ragozin S, Jeltsch A. The UHRF1 protein stimulates the activity and specificity of the maintenance DNA methyltransferase DNMT1 by an allosteric mechanism. The Journal of biological chemistry. 2014; 289(7):4106-15.
  • Bashtrykov P, Jankevicius G, Smarandache A, Jurkowska RZ, Ragozin S, Jeltsch A. Specificity of Dnmt1 for methylation of hemimethylated CpG sites resides in its catalytic domain. Chemistry & biology. 2012; 19(5):572-8.
  • Bashtrykov P, Ragozin S, Jeltsch A. Mechanistic details of the DNA recognition by the Dnmt1 DNA methyltransferase. FEBS letters. 2012; 586(13):1821-3.
  • Menshikov M, Plekhanova O, Cai H, Chalupsky K, Parfyonova Y, Bashtrikov P, Tkachuk V, Berk BC. Urokinase plasminogen activator stimulates vascular smooth muscle cell proliferation via redox-dependent pathways. Arteriosclerosis, thrombosis, and vascular biology. 2006; 26(4):801-7.
  • Furnkranz A, Schober A, Bochkov VN, Bashtrykov P, Kronke G, Kadl A, Binder BR, Weber C, Leitinger N. Oxidized phospholipids trigger atherogenic inflammation in murine arteries. Arteriosclerosis, thrombosis, and vascular biology. 2005; 25(3):633-8.


  • Laborübung „Biochemische Methoden für Fortgeschrittene“
  • Seminar „Genregulation, Chromatin und Molekulare Epigenetik“


  • Genregulation, Chromatin und Molekulare Epigenetik
  • Forschungspraktika, B.Sc. und M.Sc. Arbeiten

Education and Career

  • 2015-present: Group leader, Department of Biochemistry, Institute of Biochemistry and Technical Biochemistry, University of Stuttgart, Germany
  • 2014-2015: Postdoctoral position at the Institut of Biochemistry, University of Stuttgart, Germany
  • 2014: Dr. rer. nat. (Biochemistry), summa cum laude
  • 2010-2014: Doctoral studies at Jacobs University, Bremen and at the Institut of Biochemistry, University of Stuttgart, Germany
  • 2007-2010: Clinical Research Associate, Qintiles GmbH
  • 2002: Invited Scientist, Medical University of Vienna, Department of Vascular Biology and Thrombosis Research, Vienna, Austria
  • 1999-2006: Research Assistant, Russian Cardiology Research Centre, Department of Molecular Endocrinology, Moscow, Russia
  • 2003: Diploma in Medicine
  • 1997-2003: Study of Medicine, Moscow State University, Moscow, Russia
To the top of the page