Prof. Jeltsch is editor of a Special issue "Role of DNA Methyltransferases in the Epigenome" in the journal "Genes"
DNA methylation, a modification found in most species, regulates chromatin functions in conjunction with other epigenome modifications, such as histone post-translational modifications and non-coding RNAs. In mammals, DNA methylation has an essential role in development by orchestrating the generation and maintenance of the phenotypic diversity of human cell types. Recent years have brought spectacular advances in our understanding of the mechanism, function and regulation of DNA methyltransferases through their interaction with other epigenome modifications, chromatin factors and post-translational modifications. This Special Issue of genes covers aspects of epigenome regulation by DNA methyltransferases, fomr biochemical, genetic and cell biological perspective, as well as the crosstalks between DNA methyltransferases and other marks of the epigenome network.
genes (ISSN 2073-4425) is a peer-reviewed open access journal of genetics and genomics published monthly online by MDPI (Impact Factor: 3.191). his special issue belongs to the section "Molecular Genetics and Genomics".