DNA Methyltransferases - Role and Function
Dr. Renata Jurkowska and Prof. Albert Jeltsch edited a book on the role and function of DNA methyltransferases, important enzymes in a broad range of organisms with several clinical connections. In 19 chapters, many of them written by leading experts, the book describes biochemical properties of these enzymes, including their structures and mechanisms. It also explains the biological processes of reading of DNA methylation and DNA demethylation. It covers many emerging aspects of the biological roles of DNA methylation functioning as an essential epigenetic mark and describes the role of DNA methylation in diseases. Moreover, the book explains modern technologies, like targeted rewriting of DNA methylation by designed DNA methyltransferases, as well as technological applications of DNA methyltransferases in DNA labelling and it summarizes recent methods for the analysis of DNA methylation in human DNA.
DNA Methyltransferases - Role and Function Book series: Advances in Experimental Medicine and Biology DOI: 10.1007/978-3-319-43624-1 Hardcover ISBN: 978-3-319-43622-7 Publisher: Springer International Publishing 535 pages
This book was one of the top 25% most downloaded eBooks in 2017 in the relevant eBook Collection of Springer-Nature.