Open positions for PhD students
In the Department of Biochemistry of University Stuttgart (Germany), a doctoral position is available.
Epicircuit - Design of synthetic epigenetic control loops in bacteria. Recently, we described the design of synthetic epigenetic switches that can capture transient environmental signals and store that information in bacterial cells in the form of DNA methylation patterns. In this project, the applicability of artificial epigenetic circuits should be improved and their switching characteristics better understood. Methods of synthetic biochemistry and quantitative dynamic modeling will be used to gain a mechanistic understanding of regulatory principles, information processing and epigenetic storage, increase their performance and complexity, and capture additional input signals. The project will be funded by a DFG-funded cooperation with Prof. Dr. med. N. Radde (Institute of Systems Theory and Control Engineering, University of Stuttgart).
Maier et al. (2017) Nat Commun. 8:15336
Maier & Jeltsch (2018) Methods Mol Biol. 1867:29-41
Ullrich et al. (2020) PLOS ONE, 15:e0232701
The position is to be filled first for 3 years at salary level TVLE13 (50%). We offer a scientifically active environment at the interface of Biochemistry, Molecular Epigenetics and Synthetic Biology, modern facilities and a good working atmosphere. We expect high engagement, excellent degrees and relevant experimental experiences.
Applications should only be sent electronically with motivation letter, current credentials, contact addresses for references, CV and a compilation of the project-relevant experimental knowledge to Prof. Dr. Albert Jeltsch at
B.Sc. and M.Sc. thesis projects
We are always looking for engaged and interested students of Technical Biology or Chemistry (or qualified external applicants) for scientifically oriented B.Sc. and M.Sc. thesis projects.