Prof. Marianne G. Rots and Prof. Albert Jeltsch edited volume 2 of their book on Epigenome Editing. This second volume details new and updated methods covering applications of epigenome editing. Chapters guide readers through general and topical reviews, DNA-binding devices, optimization of the effector domains, readout of epigenome marks, and approaches for delivery at the cellular and organismal level. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
Information about the book:
Epigenome Editing - Methods and Protocols (Edition 2)
Serie: Methods in Moleclar Biology (Band 2841)
DOI 10.1007/978-1-0716-4051-7
Hardcover ISBN: 978-1-0716-4050-0
Springer International Publishing
Contributions of IBTB authors to the book
- Rots MG, Jeltsch A. (2024) Development of Locus-Directed Editing of the Epigenome from Basic Mechanistic Engineering to First Clinical Applications. DOI 10.1007/978-1-0716-4051-7_1
- Rajaram N, Bashtrykov P, Jeltsch A. (2024) Protocol for Allele-Specific Epigenome Editing Using CRISPR/dCas9. DOI 10.1007/978-1-0716-4051-7_9
- Knodel F, Pinter S, Kroll C, Rathert P. (2024) Fluorescent reporter systems to investigate chromatin effector proteins in living cells: Applications and protocol. DOI 10.1007/978-1-0716-4051-7_12
- Albrecht C, Bashtrykov P, Jeltsch A. (2024) Amplicon-Based Bisulfite Conversion-NGS DNA Methylation Analysis Protocol. DOI 10.1007/978-1-0716-4051-7_21
Contact
Albert Jeltsch
Prof. Dr.Head of Biochemistry Department and Acting Director of the IBTB
Philipp Rathert
PD Dr.Lecturer and group leader