The Dnmt1 DNA Methyltransferase plays an important role in the copy process of DNA methylation patterns. Our results on the mechanism of this enzyme have been described in a recent press release of the University.
Specificity of dnmt1 for
methylation of hemimethylated CpG sites resides in its catalytic domain. Bashtrykov P, Jankevicius
G, Smarandache A, Jurkowska RZ, Ragozin S, Jeltsch A. Chem Biol. 2012, 19(5):572-8.