New publication in "J. Mol. Biol."

August 28, 2013 /

Reading domain for histone variant discovered

In a new publication in "J. Mol. Biol.", we report that the Tudor domain of the PHF1 protein specifically interacts with a modified histone H3 variant.  This is the first example of a specific readout of the modification state of a histone variant. It opens new fields of chromatin regulation by the incorporation of histone variants and their specific modification.

PubMed Link

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