2 nd edition of book on DNA Methyltransferases published
The second edition of the Springer/Nature book on DNA methyltransferases with Prof Jeltsch as co-editor has been published. The book has been comprehensively updated to reflect many novel research findings regarding the structure, function, and technology of these enzymes that have emerged over the past 6 years. As the previous edition, this 2 nd edition explains the biochemical properties of DNA methyltransferases, describing their structures, mechanisms and biological roles in bacteria, humans and plants. It also discusses the biological processes of reading DNA methylation and the mechanisms of DNA demethylation. This volume highlights the newest findings on DNA methyltransferase inhibitors and their use in cancer therapy as well as the latest epigenome editing systems based on these enzymes. Overall, this 2 nd edition comprehensively summarizes the current state of research in the field of DNA methylation and DNA methyltransferase and is essential reading for early career and advanced researchers in this exciting field.
Albert JeltschProf. Dr.
Head of Biochemistry department and acting director IBTB